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Enzyme Linking Fatty Acids to Alpha-synuclein Could Be Parkinson’s...

Inhibiting an enzyme that regulates the production of fatty acids may protect against brain toxicity induced by alpha-synuclein in Parkinson’s disease and may become a therapeutic target for these...

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Lewy Bodies Are Made of Much More than Alpha-Synuclein, Study Finds

Insoluble alpha-synuclein protein has long been thought to be the main component of Parkinson’s hallmark Lewy bodies, but researchers have now reported these abnormal aggregates are also made of cell...

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New MRI Technique Can Visualize Brain Molecular Composition, Study Shows

A new magnetic resonance imaging (MRI) technique allows for the visualization of molecular changes in the brain, a study reports. This technique will allow researchers to further understand how the...

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Imbalance of Fat Content in Brain Cells May Fuel Parkinson’s Progression,...

In patients with Parkinson’s disease, dopamine-producing neurons and microglia cells — the “immune cells” of the brain — accumulate fatty molecules that may promote inflammation and disease...

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Changes to Nerve Cell Membrane May Promote Alpha-synuclein’s Toxic Turn

Changes in the composition of fat molecules on the membranes of nerve cells appear to change how the alpha-synuclein protein interacts with these same cell membranes, possibly promoting the aggregation...

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